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OBJECTIVES
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OPPORTUNITIES
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RESOURCES IN KARNATAKA
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THE BIOTECH INDUSTRY
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SPECIFIC INFRASTRUCTURE FOR THE DEVELOPMENT OF
BIOTECHNOLOGY
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GENERAL INFRASTRUCTURE FOR THE DEVELOPMENT OF
BIOTECHNOLOGY
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HUMAN RESOURCE DEVELOPMENT IN BIOTECHNOLOGY
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BIOINFORMATICS
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INSTITUTIONAL FRAMEWORK FOR PROMOTING
BIOTECHNOLOGY
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Hon'ble Chief Minister,
Mr. S. M. Krishna in his budget speech for the year 2000-2001 has said,
"While Karnataka is the
acknowledged leader in IT, I would like the State to lead the next revolution
in Biotechnology. Karnataka already has the training and knowledge base
necessary to drive the revolution. We have the critical mass of biotech
companies and the best research institutions. The immediate challenge is how to
nurture that innovation, promote entrepreneurship and facilitate effective
technology transfer to the end users. I am happy to announce a Vision Group on
biotechnology is being set up to advise the government on future strategies."
As promised in the
budget speech by the Hon'ble Chief Minister, the government has already set up
a Vision Group on Biotechnology. Now, the Government of Karnataka is pleased to
announce the Millennium Biotech Policy.
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OBJECTIVES
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The objectives of the Millennium Biotech Policy are:
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To spread awareness
about the investment opportunities in biotechnology, genomics, bioinformatics,
biofuels, contract research, etc., to the entrepreneurial community.
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To sustain and maintain the present pre-eminent position of Karnataka and
Bangalore in the field of biotechnology.
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To outline a set of incentives and concessions for the biotechnology industry
to attract investments to the State.
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To provide specific infrastructure as well as enhance human resources for the
development of biotechnology.
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To encourage the growth of bioinformatics in Karnataka.
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To provide an appropriate institutional framework to achieve all these
objectives.
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OPPORTUNITIES
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The
opportunities in Biotechnology are numerous and multi-faceted. They are also
growing in diversity and market value very rapidly.
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Genomics |
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The
Human Genome Project (HGP) was the first mega project in biology, involving
international participation and public and private partnership.
The HGP
has deciphered the existence of 30,000-40,000 genes, less than half the
originally predicted 100,000 genes. This, therefore, points to multifunctional
genes expressing several proteins, each acting in intricate networks. This has
thrown open immense challenges and opportunities in functional genomics and
proteomics. India is in a unique position to harness this opportunity through
researching its vast and varied disease populations in conjunction with its
human diversity. The opportunities and challenges will therefore revolve around
mining these large databases for new knowledge, and for creating economic
value.
A concerted effort in
this area provides promising high value products and technologies in disease
diagnostics and therapies on a pharmacogenomic platform. Indications already
exist in Indian gene pools to provide new information on breast and colon
cancer, asthma, diabetes and a host of other disease segments.
Another
emerging area is that of differentiated diseases by the way of disease subsets
e.g. five different genetic aberrations causing asthma, which calls for five
different treatments. Here tissue characterization and pharmacogenomic studies
play key roles where two cancers which appear similar under a microscope
respond differently to treatment regimes. This enables targeted drug discovery
to occur instead of the trial-and-error methods currently used to generate new
drug molecules.
The
genomics area can be segmented as follows: (i) Reagent and chip companies; (ii)
Tools and Bioinformatics companies; (iii) R&D and contract research
companies; (iv) Product and therapy companies.
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Biofuels |
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The world is
experiencing an energy crisis. The search for alternative fuels has been on for
long. Biofuels offer an attractive opportunity to conserve and economise
conventional fuels like petrol and diesel. Biofuels are being used the world
over as admixtures with conventional fuels at levels that do not require
modifications of IC engines. Pure biofuels can also be used. However, this
requires a modification of IC engines. In general, blends containing 25%
biofuels can be effectively used, resulting in lower cost of fuels (50% the
cost of petrol) with low polluting emission characteristics.
Brazil
is the leader in biofuel usage, where biofuels have been used in automobiles
for over 25 years. Brazil currently produces 13 billion litres of bioethanol
from sugarcane, fuelling over 3.5 million vehicles on pure ethanol. The rest of
the vehicles run on 75-80% blends of ethanol and gasoline.
In the
latter part of 2000, Thailand announced 40 new ethanol plants in addition to
the existing 22 plants to produce 3 billion litres of ethanol for use as
automobile fuel. The Bangkok Mass Rapid Transport Authority currently uses
ethanol-blended fuels containing 15% ethanol in all public vehicles.
Karnataka
has a vast and vibrant sugar industry. Sugarcane is grown in an area of
2,30,300 hectares in the State and 22 million tonnes of sugarcane is produced
annually. The total sugar production in Karnataka is 1.7 million tonnes.
Sugar
factories in Karnataka produce 600,000 tonnes of molasses annually, most of
which is converted by distilleries to produce rectified spirits and eventually
into potable alcohol. Sugarcane farmers experience large fluctuations in prices
depending on the crop yields. A poor year pushes the prices up, resulting in
farmers planting more sugarcane. However, this results in an imbalance in
supply and demand, leading to a glut the following year, with sharply declining
prices. There is need to encourage greater cultivation of sugarcane and to
provide commensurate demand. Biofuels offer the ideal solution to the
aforementioned problem. The Karnataka State, therefore, proposes to support the
setting up of biofuel plants so that surplus molasses can be converted to
biofuels. This will help to achieve a dual benefit of cost savings as well as
of a cleaner fuel with a positive impact on the environment. The Excise
Department will work out the detailed guidelines for this sector.
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Contract Research
Organisations |
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The trend to outsource
low cost R&D capabilities in biotechnology is increasing. This represents a
tremendous opportunity for Indian companies to do contract research for
overseas corporations. The current global spend on outsourced R&D is
approximately $7 billion and is expected to grow at 30% per annum for the next
5 years. Typically, opportunities exist in basic gene sequencing work, cDNA
library preparation, genetic research related to medical diagnostics, new crop
varieties and early stage drug development. Large multinational corporations
follow a strategy of subcontracting parts of their R&D programmes to
smaller and lower cost companies and derive benefits in costs as well as time.
Companies in Bangalore with excellent technical manpower are well suited to
take up such contract research. Apart from these companies, MNCs also have the
benefit of world-renowned institutions such as IISc, NCBS, JNCASR etc. located
at Bangalore, which enhances the contract research dimension in Bangalore.
The key
stakeholders in this segment would be pharma companies, entrepreneurs, research
institutions (public & private), R&D facilities, funding agencies and
educational institutes.
Contract
Research Organisations (CROs) have great potential to function as export
oriented units and are comparable in their activity to the software development
activities in the IT sector. Software services were outsourced by the large
overseas IT companies in a very similar manner, starting initially with the
sub-contracting software development of small modules of complex software and a
decade later, the Indian IT sector is now capable of handling the entire
software, the primary reason for the prolific growth in the IT sector. Contract
research in Biotechnology offers the same template of growth and the Government
of Karnataka is firmly committed to supporting these organisations.
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The chart below shows
the typical role of a CRO.
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TOP
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RESOURCES IN KARNATAKA
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Corporates in
Biotechnology |
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Karnataka
has a large number of biotech companies, ranging from start-ups to well
established concerns such as AstraZeneca India, Biocon India, Cadilla,
SmithKline Beecham and Wockhardt. For more names, please refer to the inside
back cover of this brochure.
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| Premier
Institutions in Karnataka |
The
premier position of Bangalore in the knowledge segment has been due to its
strong tradition in education and in science and technology. Institutions
dedicated to, or with strengths in, the biological sciences include: the Indian
Institute of Science, National Centre for Biological Sciences (TIFR), NIMHANS,
Jawaharlal Nehru Centre for Advanced Scientific Research, Central Food
Technological Research Institute (Mysore), Kidwai Memorial Institute of
Oncology, Manipal Institute for Neurological Diseases, Rajiv Gandhi University
of Health Sciences and the University of Agricultural Sciences.
The
physical science oriented institutions include the Raman Research Institute,
Indian Space Research Organization, Indian Institute of Astrophysics, National
Aerospace Laboratories, and Electronic and Radar Development Establishment. The
premier National Law School of India University and an Indian Institute of
management are also located in Bangalore.
Karnataka
has around 82 engineering colleges, 23 medical colleges, 46 pharmacy colleges,
almost 200 polytechnics and 300 industrial training centres.
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| Indian
Institute of Science |
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The Indian Institute of Science (IISc) was established in the
days of the Maharaja of Mysore in collaboration with Tatas in 1909. The Indian
Institute of Science has been ranked as the 18th best university in the world.
The institute has a number of departments in various areas of biology and
biotechnology: Bio-Chemistry, Micro Biology & Cell Biology, Molecular
Reproduction, Development & Genetics, Molecular Biophysics, and Ecological
Sciences.
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Jawaharlal Nehru Centre
for Advanced Scientific Research |
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The
Centre was established in 1989 by the Department of Science and Technology to
commemorate the birth centenary of Pandit Jawaharlal Nehru. The Institute has
been set up by Prof. C.N.R. Rao and has close links with the Indian Institute
of Science. The Institute's main objective is to promote scientific research at
the highest level in frontier and disciplinary areas of science and
engineering. In the biological sciences, it has an Evolutionary and Organismal
Biology Unit, a Molecular Biology and Genetics Unit, as well as, in
collaboration with IISc, a Chemical Biology Unit.
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| National
Centre for Biological Sciences |
The
National Centre for Biological Sciences (NCBS), Bangalore is a new centre of
the Tata Institute of Fundamental Research, Mumbai. It is located in north
Bangalore, on the campus of the University of Agricultural Sciences. The
mandate of NCBS is basic research in frontier areas of biology. The research
interests of the faculty are in the following areas: Biochemistry, Biophysics &
Bioinformatics, Genetics & Development, Cellular Organisation & Signaling, and
Neurobiology. The centre has Ph.D., Integrated Ph.D. and Physics-in-Biology
Ph.D. programmes.
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| Biotechnology
Centre
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The
Centre, located on Bannerghatta Road, is the first of its kind in the country
in the public sector, aiming at integrating all spheres of biotechnology for
the cause of horticulture development. The activities of the centre include:
large scale cloning, in vitro conservation, crop improvement, quality control
facilities for biofertilizers, biocontrol agents and biopesticides, residual
analysis of chemical pesticides and fertilizers, soil, water and leaf analysis,
training in mushroom handling & processing and dissemination of information on
horticultural biotechnology.
The
various research institutes in Bangalore have sophisticated state-of-the-art
facilities in biotechnology including a modern primate surgical theatre,
capillary DNA sequencers, CCD-based quantitative fluorescence imaging
facilities, confocal microscopes, DNA and protein sequencing facilities, FACS
scan-flow cytometers, ecological field research facilities, hybridoma and
tissue culture facilities, IVF and embryo-culture facilities, molecular
modelling and visualization packages, monoclonal antibody facilities, optical
spectroscopes, rapid mixing machines for millisecond measurement, sequence
submission, searching and retrieval packages.
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Bangalore - The IT
Capital of India |
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Bangalore
is appropriately called the IT Capital of India. The city has over 21
engineering colleges, which is the highest in the world; over 75,000 IT
professionals and over 900 software export companies. Over 125 multinational
companies are located here. Bangalore is known for its Integrated Chip Design
Software, telecom software as well as system software. The city also boasts of
excellent quality companies: 12 out of 22 SEI CMM Level 5 companies in the
world are located in Bangalore.
The city
offers one of the best telecom connectivity in India. The connectivity is
presently available via VSNL as well as STPI. The state has already announced
its free right of way policy and several private companies have already laid
1800 kms of fibre optic cable. In the next few months, we expect connectivity
from a few of these private players also.
Karnataka
has unparalleled human resources in various areas of technology. The state
accounts for about 15% share of higher education in the country. It is also the
pioneer in liberalising higher education: Out of the 82 engineering colleges,
only 2 are in the government sector.
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| Venture Capital in
Bangalore |
Bangalore has all the
ingredients for a successful incubation in both information technology and
biotechnology. It has excellent companies, world-renowned institutions and
research centres as well as venture capital funds. Some of the venture funds
that are operating in Bangalore are listed below.
APIDC
Venture Capital, Canbank Venture Capital, Gujarat Venture Capital, IDBI Venture
Capital, IFB Venture Capital, IFCI Venture Capital, Industrial Venture Capital,
KITVEN Fund, Marigold Advisors, SICOM Venture Fund, SIDBI Ventures, UTI
Ventures, Alliance Venture Capital, Barings Pvt. Equity, Chrysalis Capital,
Global Tech Ventures, HSBC Private Equity, ICF Ventures, Indus Venture
Management, JF Electra, Jumpstartup Advisors, KVP Ventures, Pathfinder
Investment, Ant Factory, Blueshift Ventures, e4e Labs, SIFY Innovations,
Indchem/Silkroute, 2i Capital, Connect Capital, Dhunn Carr, eIndia Capital,
Hexagram Fund, iNestor, Newbridge Capital, Passion Fund, Q5 Capital, AIG
Capital, Alchemy Ventures, Bank of America, Carlyle Fund, CDC Advisors, Chase
Capital, Citibank Pvt. Equity, Deutche Bank, eVentures, Gary Wendt Capita, GE
Capital, Global Internet Ventures, ICICI Eco Net, ICICI Ventures, IDEA, IFC,
Washington, IL& FS Venture Corporation, Ind Asia Fund, Infinity Capital, Intel
Corporation, Kotak Mahindra, Morgan Stanley, Schroeders, Vertex Management,
VIEW Group, Walden, Warburg Pincus, Westbridge Capital.
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TOP
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THE BIOTECH INDUSTRY
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Definition of a Biotech
Company |
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A
Biotechnology Company means and includes inter-alia a company engaged in any of
the following activities:
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Research & development
and/or manufacture of products or processes, which use or are derived by using
specific living systems, and or enzymes/biocatalysts derived therefrom.
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Genetic engineering or
cell culture or microbiology or biochemistry
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Bio-informatics.
Note: "Living
system" would include plants, animals and microbes. "Biocatalyst" would mean
proteins or proteinaceous molecules naturally occurring in or derived from
living systems whose primary function is to assist in biochemical reactions.
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| Taxation on
Biotechnology Products |
The
Government of Karnataka's stand on the taxation of the biotechnology products
is similar to that on the information technology products. In fact, the
Government of Karnataka believes that the knowledge based industries like
information technology and biotechnology should not be taxed for next 3-5
years. Relevant extract of the Hon'ble Chief Minister's speech at the first IT
Minister's Conference that was held in Delhi on 15 July 2000 is reproduced
below. This conference was attended by 14 Chief Ministers and was chaired by
the Hon'ble Prime Minister.
"In this
connection, I request the Prime Minister, the Union Minister of IT and my
esteemed colleagues to intervene and ensure that the government will keep the
IT sector out of the ambit of all taxation measures for the next 3-5 years."
However,
the Government of Karnataka to abide by the decisions of the empowered
committee of State Finance Ministry on Tax Reforms, constituted by the Ministry
of Finance, Government of India.
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| Fiscal Incentives |
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The
biotechnology industry will be exempt from the payment of entry tax on all
inputs as well as capital goods, including captive generation sets, during the
implementation stage, which can be up to 5 years or during the construction
period whichever is earlier.
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Mega Projects |
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Mega
projects will be offered a unique package of concessions including concessions
stated elsewhere in this policy, for a maximum period of 8 years. They will
also be offered upto 50% concession on stamp duty and registration charges for
first sale and first lease. A mega project will be one which will have
investment of more than Rs. 50 crores in a new company or in the expansion of
an existing company, or which will provide employment to 250 in Bangalore or to
100 in any other city in the State of Karnataka. The concessions will be
applicable to new investors as well as to any such company that creates
employment from incremental investment.
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| Captive
Generation |
Captive
generation sets installed by the biotechnology industry will be eligible for
the following incentive:
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| Safeguards |
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In order
to establish a biotechnology unit, the entrepreneur must fulfill various
requirements depending on the specific nature of the unit. These requirements
are those of the (i) State Pollution Control Board (SPCB), (ii) Hazardous
Wastes (Management and Handling) Rules, 1989, (iii) Manufacture, Storage and
Import of Hazardous Chemical Rules, 1989, (iv) Rules for the Manufacture, Use,
Import, Export and Storage of Hazardous Micro-organisms, Genetically Engineered
Organisms or Cells, (v) Genetic Engineering Approval Committee (GEAC), New
Delhi, (vi) Public Liability Insurance Act, (vii) Environmental Impact
Assessment Notification, 1994, (viii) Radiological Physics and Advisory
Division etc. Details are available on the web site
www.bangalorebio.com.
In
addition, the Biotechnology Coordination Committee (BCC) shall monitor the
safety regulations in installations engaged in the use of genetically modified
organisms/hazardous microorganisms and their applications in the environment.
The district level committees shall visit such installations, formulate
information charts, as certain hazards and risks and coordinate activities with
a view to meeting any emergency.
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Power |
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Biotech
companies will be treated as industrial, not commercial consumers and the
relevant electricity tariff will be levied on such companies. Uninterrupted and
quality power supply being one of the prime requirements for sustenance and
growth of biotechnology industries, these industries will be given priority in
sanction and servicing of power and will also be exempt from power-cuts without
any time limit.
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| Zonal
Regulations |
Bioinformatics
companies that use up to 5 KVA power will be permitted to be established
without any locational restrictions. The companies can be established in
residential, industrial or commercial areas.
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| Urban
Development |
|
The
government is pleased to relax FAR for all biotech projects set up outside the
limits of the municipal corporations in the state. This concession will be
available to projects notified by the Department of IT and Biotechnology. A
maximum relaxation of up to 50% of the existing FAR will be available to such
projects.
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| Venture
Capital |
The
biotechnology industry is in the initial stages and requires active monetary
support from the Government. Accordingly, the government will encourage setting
up of venture capital funds for biotech industries with private participation.
It may also be noted that the state has several major financial/VC players, as
in section 4.13.
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Registration Charges |
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Karnataka
recognizes the potential of biotech companies to create new employment
opportunities. All new biotech companies, which create employment of more than
100 in Bangalore and 50 in other areas in the State during the first year, will
be eligible for rebate either on the stamp duty or rebate on the cost of the
land. A rebate of 15% on the cost of the land will be applicable to those
companies that get land from the state agencies like Karnataka State Small
Industries Development Corporation, Karnataka Industrial Areas Development
Board, KEONICS etc. For other companies rebate of 50% on stamp duty and
registration charges on first sale/lease transactions are applicable. This
rebate on stamp duty is also applicable to the existing biotech companies
expanding or modernizing, as well as creating additional employment as stated
above.
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| Concessions
for Creating Employment |
Pre-existing
tiny and small-scale industries taking up expansion, diversification and
modernization get a concession on registration charges. These companies pay
nominal stamp duty on lease-cum-sale deeds executed with State Government
agencies like Karnataka State Small Scale Industries Development Corporation,
Karnataka Industrial Areas Development Board, KEONICS, etc. Even when the
absolute sale deeds are executed, the stamp duty depends on the consideration
amount agreed upon at the time of leasing. These concessions are also
applicable for companies in the biotech sector.
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| Labour
Laws Simplified |
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Section
11 of the Shops and Commercial Establishments Act 1951 restricts the opening
and closing times of any establishment and Section 12 requires closure of the
establishment on one day of the week. Section 25 of the Act prohibits
employment of women at night. The Government approved an amendment to
sub-section (2) of Section 3 of the Act. This amendment will put the IT
industry outside the scope of section 11 and 12 of the Act. An amendment to
Section 25 is also approved enabling the IT sector to employ women at night.
The said benefit would also be made applicable to the biotechnology industry.
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TOP
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SPECIFIC INFRASTRUCTURE FOR THE DEVELOPMENT OF BIOTECHNOLOGY
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Biotech Parks |
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Karnataka
is a pioneering state where several international standard IT Parks have
already been established. The International Technology Park Ltd. was
established through a joint venture of the Government of Karnataka, the TATA
group and Singapore Consortium. The Institute of Bioinformatics and Applied
Biotechnology as well as Avesthagen Technologies are located here.
The
Government of Karnataka would like to encourage such hi-tech parks in the
biotech sector too. The following concessions are offered to the Biotech Parks.
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Exemption on payment of
Entry Tax on machinery, equipment, capital goods and construction materials,
for a period of 3 years or till the date of completion of the project,
whichever is earlier, on condition that each invoice should not be less than
Rs. 25 lakhs or Rs. 10 lakhs in case of construction materials.
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Upto 50% exemption from
the payment of stamp duty and registration charges.
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In case of first lease,
as well as a subsequent lease of biotechnology companies, concessions will be
available for biotechnology parks certified by the Department of IT and
Biotechnology. Such parks should have a minimum built up area of 50,000 sq. ft.
The
first Biotech Park will be established on the campus of the University of
Agricultural Sciences, Bangalore. About 30 acres of land will be handed over to
the Department of IT and Biotechnology for this purpose. This international
standard park will have reputed R&D institutions, biotech companies and
incubation facilities, etc. The entire management of the park will be under the
guidance of the Vision Group on Biotechnology. The facilities shall be
primarily on commercial lines.
The
Department of IT & Biotechnology will establish another Biotech Park in the
Karnataka University, Dharwad, where about 15 acres of land shall be made
available.
The Department of
Fisheries/University of Agricultural Sciences, Dharwad will establish a Marine
Biotech Park at Karwar for promoting research in marine Biotechnology.
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| Biotech
Corridor |
The
Government of Karnataka is committed to establish a Biotech Corridor for the
development of the biotech industry in Karnataka. The Corridor in Bangalore
shall extend from the Indian Institute of Science to the University of
Agricultural Sciences.
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|
Centre For Human
Genetics |
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The
Centre for Human Genetics is being set up in Bangalore with leading scientists
and science policy makers on its Governing Board. Its Director, H. Sharat
Chandra, is Chairman of the Task Force on Human Genetics and Genomics of the
Department of Biotechnology, New Delhi. The Centre will bring together a group
of highly talented Indian scientists to join the ongoing revolution in our
understanding of human genes - their nature, organization, evolution and their
relationship to disease - and, in the process address the existing lacunae in
research, education and technology. Suitable land, and a corpus grant will be
made available to this institute.
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| Institute of
Agri-biotechnology |
An
Institute of Agri-biotechnology will be set up in Dharwad by the Department of
Agriculture with the active collaboration of the University of Agricultural
Sciences. The institute will be housed in the buildings of the university
itself, and a special grant of Rs. 5 crores will be made available to set up
and run this institute. The institute will primarily be set up for the
application of biotechnology in the agricultural sector, with a focus on
productivity improvement. The institute will be managed by the Department of
Agriculture.
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| K-Ganga |
The
Karnataka Global Advisory Networking Group on Agriculture has already been
announced. This initiative, headed by C.S. Prakash, will comprise leading
agriculture scientists from Karnataka who are presently working in the U.S.A.
and other developed countries. This network of global advisers will focus
attention on the applications of biotechnology in the agricultural sector. The
Institute of Agri-biotechnology and the Department of Agriculture will service
K-Ganga.
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TOP
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GENERAL INFRASTRUCTURE FOR THE DEVELOPMENT OF BIOTECHNOLOGY
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|
Bangalore International
Airport |
|
The
state has already made available over 4000 acres of land for the location of an
International Airport near Bangalore. Of the 7 bidders who applied, 2 have been
short-listed. The government has formed the Bangalore International Airport
Company Ltd. headed by Mr. N.R. Narayana Murthy, Chairman, Infosys Technologies
Ltd. This company is finalising the bids, and construction of the airport is
expected to start soon. A six-lane highway will connect Bangalore city to the
airport.
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| Bangalore
Agenda Task Force |
The
government has constituted Bangalore Agenda Task Force (BATF) headed by Mr.
Nandan Nilekani, Managing Director, Infosys Technologies Ltd. This is one of
the efforts of the government to actively involve the private sector in
planning for, and providing infrastructure for citizens. The BATF has already
suggested several measures to improve critical infrastructure. The government
is committed to honour and involve private initiatives to improve the
infrastructure and standard of living of its citizens.
|
| World
Bank - HUDCO Assistance |
The
State, with the assistance of World Bank and HUDCO, has plans to spend over Rs.
12,000 crores over the next few years on infrastructure projects. For instance,
the Road Development Corporation is expected to spend Rs. 650 crores on
improving Karnataka roads. The government plans to spend Rs. 3000 crores on the
power sector. Initiatives in this sector include unbundling of entities,
rationalization of tariffs, privatization of distribution and new generation
projects. A further Rs. 950 crores will be spent in improving urban
infrastructure. Many other infrastructure projects viz., the Bangalore Mass
Rapid Transit System, the Bangalore-Mysore Express Highway, the
Mangalore-Bangalore Petro Product Pipeline, etc. are also planned.
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HUMAN RESOURCE DEVELOPMENT IN BIOTECHNOLOGY
|
|
The
biotechnology industry, including bioinformatics, pharmaceuticals, agriculture,
natural products, marine biotechnology, health care, etc., is poised for major
expansion worldwide. In India, students need to be trained in modern and
integrative aspects of biology, to better prepare themselves for careers in
this industry. Karnataka has several universities and other research
institutions offering advanced degrees in areas of the biological and physical
sciences. However, these courses are specialized, not integrated. Also, there
is a long time lag for updating syllabi compared to the pace of change in each
field. The following measures will be taken to accelerate the development of
Karnataka's human resources in this rapidly evolving area.
|
| Scientific
Computing |
The
largest single gap in the biology student's expertise is in scientific
computing. Students need to know word processing, programming, spreadsheet use,
networking and hardware. Each of these is individually taught in many computer
training institutions. It may be best for science programmes to recommend a set
of existing courses, such as those at reputed computer training institutions;
at Yuva.com which is a new IT-training scheme of the Government of Karnataka;
or at the IT courses in colleges, which could be counted for credits. Colleges
will be encouraged to enter into reciprocal arrangements with computer training
organisations to provide computer instruction in exchange for space and similar
institutional resources. The Government will also formulate a scheme that
encourages scientific computing for biology students.
|
| Electronic
Education |
|
Faculty
at the universities and research institutions are primarily geared to research
and to teaching their post-graduate and Ph.D. students. Using multimedia
recordings of specialised topics and an internet or CD-based distribution
network, we could reach a much wider audience of students (diploma or
undergraduate onwards) with little extra effort on the part of the researchers
in these institutions. Such lectures are taught fresh every year in these
institutions, and incorporate all the new material in these rapidly changing
areas. The Government will encourage such courses in consultation with
industry.
A
committee under the chairmanship of G. Padmanabhan, IISc, with the Secretary,
Higher Education and representatives of leading universities and research
institutions, as members will be constituted. The inputs of industry leaders,
entrepreneurs and research faculty will be sought in developing modern and
meaningful syllabi in the new era of expanding opportunities in the
biotechnology sector.
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TOP
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BIOINFORMATICS
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|
Biological
research has expanded from in vivo and in vitro experimentation to include in
silico experimentation, a development that relies heavily on bioinformatics.
Three
developments have caused bioinformatics to take off: the "tidal wave" of
information regarding gene and protein sequences, the availability of mini-and
bench-top computers, and the popularization of the Internet. Aside from the
draft version of the Human Genome Project, many other organisms' genome
projects are completed or in progress. Most of these relate to plant, animal
and human pathogens and such other medically and economically important
organisms.
The
effort in bioinformatics will include updating sequence information as the gaps
in the human genome are completed, annotations of gene sequence and function,
correlation with disease and variations across the population. Of even more
value to the pharmaceutical industry, similar exercises are needed at the
protein level. Data from many sources needs to be amassed, classified and
stored. They must be analyzed and annotated. Various types of data must be
presented to workers using a variety of platforms.
Sophisticated
data management and analysis tools have been developed to mine these data
resources. Other improvements in data integration and data mining will be
required to competitively transform sequence data into information that is
useful for diagnosis and development of new drugs and therapy. Thus,
bioinformatics will play a key role in the future of genomics, proteomics and
biotech education and industry.
The
success of both the IT and the Biotech industries in the U.S. has been
attributed, among other things, to the availability of high calibre scientists,
technologists and institutions in the immediate geographical vicinity.
Bangalore has the largest concentration of such institutions in the country,
both in the biosciences and in IT. Thus there are opportunities here for young
Indians to repeat the IT success story.
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Institute of
Bioinformatics and Applied Biotechnology |
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The
Government of Karnataka in association with ICICI has established the Institute
of Bioinformatics and Applied Biotechnology (IBAB) in ITPL at Whitefield,
Bangalore. H. Sharat Chandra has been nominated Chairman of this Institute.
The objectives of this
institute are:
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To offer masters and
Doctoral programs in Bio-informatics and Applied Biotechnology.
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To carry out research &
development activities in the field of bioinformatics & other related areas.
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To undertake short-term
training programmes.
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To promote and run
incubation centres for the entrepreneurs, etc.
The IBAB
expects to be financially self-sustainable through fees for start-up
incubation, contract research and its bioinformatics courses, and, in the long
run, through generation of Intellectual Property. The institute is expected to
be operational shortly. For more details, visit the website
www.bangalorebio.com.
The
Governing Body of the Institute of Bioinformatics and Applied Biotechnology
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H. Sharat Chandra,
Professor emiritus, Indian Institute of Science; Bangalore
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Kiran Mazumdar-Shaw,
Founder and CMD, Biocon Ltd.; Bangalore
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A.J.V. Jayachander
President, ICICI Venture Funds Management Company Ltd.; Bangalore
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K.Vijayraghavan,
Director, National Centre for Biological Sciences, TIFR, Bangalore
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M. A. Viswamitra,
Professor, Indian Institute of Science; Bangalore
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S. Sadagopan, Director
Indian Institute of Information Technology; Bangalore
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M. Ram Mohan Rao,
Director, Indian Institute of Management; Bangalore
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Secretary-IT
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Director-IT
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INSTITUTIONAL FRAMEWORK FOR PROMOTING BIOTECHNOLOGY
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The
institutional framework within which the objectives of the Biotechnology Policy
of the Government of Karnataka will be met are outlined below.
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| Department of
Information Technology and Biotechnology |
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The
Department of Information Technology and Biotechnology will be the Government
of Karnataka Department that will deal with matters concerning biotechnology in
the state. The Department will promote appropriate research in different
sectors, lay more emphasis on fields like bioinformatics and contract research
that are likely to create employment and will try to bring the companies and
research centres closer.
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| Funding |
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Funds
with the Department of Information Technology under the budget, as well as
raised from other sources will also be used for biotechnology.
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| Vision Group
on Biotechnology |
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A Vision
Group on Biotechnology was constituted to advise the government on policy
initiatives. Kiran Mazumdar-Shaw, a pioneer and the leader in this segment in
Karnataka, is the Chairperson. The group will be a standing feature and will
also be entrusted with several projects to manage directly. The group will be
serviced by the Department of IT and Biotechnology.
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| The Karnataka
Biodiversity Committee |
9.4 The
Government of Karnataka has constituted the Karnataka Biodiversity Committee,
with Mr. K. H. Ranganath, the Hon'ble Minister for Forest, Ecology and
Environment as the Chairman. This committee shall advise the Government on
conservation of biological diversity, on sustainable use of its components, and
to ensure fair and equitable sharing of genetic resources. Members of the
committee include Additional Chief Secretary and Development Commissioner
(Vice-Chairman), and Principal Secretary/Secretary to the Government of the
Departments of Forest, Ecology & Environment; Agriculture & Horticulture;
Fisheries & Animal Husbandry; Industries & Commerce; Health & Family Welfare;
Revenue; Law; R.D.P.R., Controller of Drugs and Principal Chief Conservators of
Forests and Principal Chief Conservators of Forests (R & W.P.).
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|
The institutional
framework within which the objectives of the Biotechnology Policy of the
Government of Karnataka will be met are outlined below. |
| Department of
Information Technology and Biotechnology |
| The
Department of Information Technology and Biotechnology will be the Government
of Karnataka Department that will deal with matters concerning biotechnology in
the state. The Department will promote appropriate research in different
sectors, lay more emphasis on fields like bioinformatics and contract research
that are likely to create employment and will try to bring the companies and
research centres closer. |
| Funding |
| Funds with
the Department of Information Technology under the budget, as well as raised
from other sources will also be used for biotechnology. |
| Vision Group
on Biotechnology |
|
A Vision Group on
Biotechnology was constituted to advise the government on policy initiatives.
Kiran Mazumdar-Shaw, a pioneer and the leader in this segment in Karnataka, is
the Chairperson. The group will be a standing feature and will also be
entrusted with several projects to manage directly. The group will be serviced
by the Department of IT and Biotechnology.
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| The Karnataka
Biodiversity Committee |
9.4 The Government of
Karnataka has constituted the Karnataka Biodiversity Committee, with Mr. K. H.
Ranganath, the Hon'ble Minister for Forest, Ecology and Environment as the
Chairman. This committee shall advise the Government on conservation of
biological diversity, on sustainable use of its components, and to ensure fair
and equitable sharing of genetic resources. Members of the committee include
Additional Chief Secretary and Development Commissioner (Vice-Chairman), and
Principal Secretary/Secretary to the Government of the Departments of Forest,
Ecology & Environment; Agriculture & Horticulture; Fisheries & Animal
Husbandry; Industries & Commerce; Health & Family Welfare; Revenue; Law;
R.D.P.R., Controller of Drugs and Principal Chief Conservators of Forests and
Principal Chief Conservators of Forests (R & W.P.).
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| Karnataka
Biotechnology Development Council |
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The Government is
pleased to announce the Karnataka Biotechnology Development Council (KBDC)
headed by the prominent scientist V. Prakash. The Council shall have the
following members:
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V.Prakash, Director,
CFTRI
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Kiran Mazumdar-Shaw,
Founder and CMD, Biocon Ltd.
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H. Sharat Chandra,
Professor Emeritus, Indian Institute of Science
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G. Padmanaban, Former
Director, Indian Institute of Science
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Kumud Sampath,
President, AstraZeneca India Pvt. Ltd.
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Villoo Morawala-Patell,
Founder and CEO, Avesthagen Technologies
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A member from the NLSIU
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Secretary, IT &
Biotechnology
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Director-IT &
Biotechnology - Member Secretary
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The
council will develop norms for setting up biotech companies. It will hold
seminars, conduct research, represent trade and interact with the Government
departments. The council will be funded by the government, by contributions
from the Biotech Fund and from other sources. The Biotech Fund was agreed to be
established in the first meeting of the Vision Group. Each biotech company is
expected to contribute 0.5% of its annual turnover to this fund. The council
will also have a number of cells that will advise biotech industries in respect
of various functional areas, some of which are described below.
Bioethics:
Each biotech company shall constitute a bioethics committee to consider ethical
and legal issues in the area of their work. Such committees shall be
constituted in consultation with the council.
Intellectual Property Rights (IPR): The council will develop a comprehensive
up-to-date database on patents, with on-line processing. It will establish an
exclusive cell to advise entrepreneurs on how to file patents and how to
protect IPR. The cell will actively interact with the National Law School, will
produce publications for use of entrepreneurs, will conduct seminars and will
advise companies on IPR management.
The council will encourage industries to adopt eco-friendly technologies: it
will conduct seminars, depute experts and spread awareness on how biotechnology
could be used towards a cleaner and greener Karnataka.
Genetically
engineered products/biodiversity: The council will provide advisory services on
how the statutory norms and procedures can be followed in these areas.
International
promotion: The council shall promote Karnataka as the most attractive
destination for biotechnology research, manufacturing and marketing. The
council shall be networked with appropriate Indian and international
biotechnology organizations and will provide a large resource base for
investors in Karnataka.
The Karnataka
Biotechnology and Information Technology Services will offer secretarial
services to the council.
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| Department Of
Biotechnology (GOI) |
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The
Government of India established this department under the Ministry of Science
and Technology in 1986. This department has given a new impetus to the
development of biotechnology in India. The unique feature of the department has
been the deep involvement of the scientific community of the country through a
number of technical task forces, advisory committees and the involvement of
individual experts in identification, formulation, implementation and
monitoring of various programmes and activities.
The Department has the
following high-powered committees:
Scientific Advisory
Committee
Chairperson:
Manju Sharma, Secretary, Department of Biotechnology, New Delhi
Members: R. A. Mashelkar, R.S. Paroda, V.S. Ramamurthy, N.K. Ganguly, N.C.
Mathur, Asis Datta, A.K. Sharma, Asha Mathur, D. Balasubramanian, H. Sharat
Chandra, G. Padmanaban, K. Dharmalingam, L.M.S. Palni, P.N. Tandon, Manmohan
Attavar, P. Balaram, R.B. Singh, Raghavendra Gadagkar, Sandip K. Basu, V.P.
Kamboj, S. R. Rao.
Scientific
Advisory Committee - Overseas
Chairperson: Manju
Sharma, Secretary, Department of Biotechnology, New Delhi
Members: Inder M. Verma, Anand M. Chakrabarty, Gurdev S. Khush, M.A.
Vijayalakshmi, Govindjee, John Kuriyan, Ganesh M. Kishore, B.M. Gandhi.
Biotechnology Research
and Promotion Committee
Chairperson:
G. Padmanaban, Former Director, IISc, Bangalore
Members: P. Balaram, Samir Bhattacharya, J.B. Choudhary, Kasturi Datta, K.
Dharmalingam, Raghavendra Gadagkar, B.N. Johri, V.P. Kamboj, Sushil Kumar, M.L.
Madan, H.Y. Mohan Ram, S.N. Puri, A.K. Sharma, R.P. Sharma, Gita Talukdar, P.N.
Tandon, H. Sharat Chandra, E.A. Siddiq, Rajiv Modi, S.K. Basu, Asis Datta, N.K.
Ganguly, V.S. Chauhan, K. VijayRaghavan, Renu Swarup, Shailaja Gupta.
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| Task Forces |
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The
department has 17 task forces that deal with Agriculture Biotechnology, Animal
Biotechnology, Basic Research in Modern Biology, Human Genetics and Genome
Analysis, Human Resource Development, Medical Biotechnology, Plant
Biotechnology, Biodiversity Conservation and Environment, Bioinformatics and
Infrastructural Facilities, Biotech Product and Process Development, Biotech
Based Programmes for SC/ST, Biotech Based Programmes for Women and Rural
Development, Aquaculture and Marine Biotechnology, Biopesticides and Crop
Management, Seribiotechnology, Food and Nutrition Security, Integrated
Nutrition Management.
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